β-irradiation (166Ho patch)-induced skin injury in mini-pigs: effects on NF-κB and COX-2 expression in the skin

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β-irradiation (166Ho patch)-induced skin injury in mini-pigs: effects on NF-κB and COX-2 expression in the skin

In the present study, the detrimental effect of β-emission on pig skin was evaluated. Skin injury was modeled in mini-pigs by exposing the animals to 50 and 100 Gy of β-emission delivered by (166)Ho patches. Clinicopathological and immunohistochemical changes in exposed skin were monitored for 18 weeks after β-irradiation. Radiation induced desquamation at 2~4 weeks and gradual repair of this d...

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ژورنال

عنوان ژورنال: Journal of Veterinary Science

سال: 2015

ISSN: 1229-845X,1976-555X

DOI: 10.4142/jvs.2015.16.1.1